New Admissions Dec 2024

Whether for quality control of food & feed or pharmacological research: PhytoLab is always working on new admissions to expand our outstanding portfolio of highly purified phyproof^® reference standards for quantitative analysis. To this end, we are constantly monitoring new regulatory requirements, scientific progress in plant constituents as well as the market situation in botanicals, herbal medicinal products, pet food and cosmetics.

Due to promising beneficial effects of Black Cumin (Nigella sativa) ^[1] and Maca (Lepidium meyenii) preparations,^[2] the interest in these products is steadily increasing in the botanicals, fortified food and pet food markets. Today we are happy to announce the addition of several important constituents of these promising herbs to the phyproofÒ portfolio in order to strengthen the capabilities of QC professionals to reliably control the identity and content of respective herbal raw materials, ingredients and finished products.

For Black Cumin, Nigelline and Thymoquinone are considered to be important contributors to its beneficial effects.^[3]

For Maca, the Lepidilines, 1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (MTCA) and Macamide B are essential markers. Only recently a new United States Pharmacopeia (USP) monograph has been proposed for Maca.^[4]

Find our substances below:

[1] K.M. Nadkarni Nadkarni’s Indian materia medica, with ayurvedic, unani-tibbi, siddha, allopathic, homeopathic, naturopathic and home remedies, appendices and indexes. 3rd ed. 1954, Bombay: Popular Prakashan; (b) S. J. Mohammed,  H. H. Amin,  S. B. Aziz,  A. M. Sha,  S. Hassan,  J. M. Abdul Aziz,  H. S. Rahman Evidence-Based Complementary and Alternative Medicine 2019, 6515671, 1-9; (c) A. Koshak, L. Wei, E. Koshak; S. Wali, O. Alamoudi, A. Demerdash, M. Qutub, P.N. Pushparaj, M. Heinrich Phytother Res. 2017, 31(3), 403-409.

[2] Bundesinstitut für Risikobewertung (BfR): Risikobewertung macahaltiger Nahrungsergänzungsmittel – Stellungnahme Nr. 024/2007 des BfR vom 3. April 2007. https://www.bfr.bund.de/cm/343/risikobewertung_macahaltiger_nahrungsergaenzungsmittel.pdf

[3] G. Burdock Regulatory Toxicology and Pharmacology 2021, 128, 105088; (b) H. Mashayekhi-Sardoo, R. Rezaee, G. Karimi Asian Biomed (Res Rev News) 2020,14(4):127-137; (c) T. Sultan, M. S. Butt, F. M. Anjum Food and Chemical Toxicology 2020, 47, 11, 2768-2775.

[4] United States Pharmacopeia (USP) (49-6). Dietary Supplement Monographs, Maca Root. USP-NF. DOI: https://doi.org/10.31003/USPNF_M4469_10101_01